11 Night U.S. Rivers Cruise

Cruise LineAmerican Cruise Lines

ShipAmerican Serenade

DepartsMon, Nov 9th 2026

ReturnsFri, Nov 20th 2026

Nights11

Departing PortMemphis

Ports of CallMemphis (2 Days), Tunica, Cleveland, Cruising the River, Vicksburg, Natchez, St. Francisville, Baton Rouge, Oak Alley, Cruising the River, New Orleans

Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Mississippi River in 2023.Like her sister ship American Symphony, the 175-passenger American Serenade introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.American Serenade also showcases panoramic views throughout, including an impressive four-story glass atrium in the center of the ship. Ranging from 250 to 650 square feet, all of the spacious staterooms offer full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service. The new ship also features an on board fitness center and many spacious lounges where you can relax after the day’s adventures.  Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…